7-bromo-1-methylimidazo[1,5-a]pyridine CAS NO.1379341-62-4

Efficient Intermediate for Heterocyclic Drug Discovery

• Bromine functional handle – ideal for Pd-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira), enabling rapid molecular diversification.

• Pharmacologically relevant scaffold – imidazo[1,5-a]pyridine core is commonly found in kinase inhibitors, antivirals, and CNS agents.

• N-methyl substitution – improves lipophilicity and modifies metabolic properties, useful in medicinal chemistry optimization.

• High chemical purity – suitable for pharmaceutical research and development.

• Versatile building block – enables synthesis of complex nitrogen-containing heterocycles and functionalized small molecules.

• Stable and easy to handle – crystalline solid with good shelf-life and compatibility in standard organic solvents.

-Bromo-1-methylimidazo[1,5-a]pyridine is a brominated nitrogen-containing heterocycle featuring an imidazo[1,5-a]pyridine fused core with a methyl substituent at the N1 position. The presence of a bromine atom at position 7 makes it an excellent substrate for palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald–Hartwig couplings.

This compound is commonly used as a pharmaceutical intermediate in the synthesis of drug candidates targeting kinases, central nervous system receptors, and antiviral pathways. Its heteroaromatic structure provides rigidity and electronic versatility, making it highly valuable in medicinal chemistry and lead optimization.

Offered in high-purity Pharma Grade, 7-bromo-1-methylimidazo[1,5-a]pyridine is ideal for research, development, and production of advanced intermediates and custom synthesis projects.